Pathology

The Pathology Laboratory at the Southwest National Primate Research Center (SNPRC) at Texas Biomedical Research Institute offers anatomic and clinical pathology services to research scientists, investigators, veterinarians and physicians at Texas Biomed and other research facilities.

SNPRC Pathology Team

Our ACVP board-certified pathologists โ€“ Edward J. Dick, Jr., D.V.M., dACVP, Olga Gonzalez, D.V.M., dACVP and Vinay Shivanna D.V.M, MVSc, PhD, dACVP, dACVM โ€“ are available to discuss laboratory results, research protocols and consult on difficult clinical cases.

What we offer

  • Necropsy procedures of primate or other species. We collect case or study specific tissues utilizing multiple techniques such as fresh, fixed, frozen, and sterile media. New methodologies can be developed upon request.
  • Histopathology, including cytopathology, OCT embedding, cryosectioning, multiplex immunohistochemistry, and RNAScope (in situ hybridization). Diagnostic interpretation, tissue scoring, microscopic evaluation, and imaging and stereological evaluation of tissue samples by board-certified veterinary pathologists.
  • Chemistry, hematology, and coagulation testing are performed on state-of-the-art instrumentation by our ASCP certified medical technologists who have over 77 years combined experience in the laboratory field.
  • Daily quality control monitoring and quality assurance programs.
  • Statistically relevant reference intervals for colony-specific species including baboons, chimpanzees, macaques, and marmosets.
  • Customized profiles:
    • Sophisticated serum banking system with archived sample.
    • Referral testing โ€“ referrals are sent to national accredited laboratories for diagnostic and research testing when in-house testing is not performed

General Service Inquiries form

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Gross dissection, all tissues

Tissue collection, multiple tissues and techniques

Tissue perfusion

Tissue fixation, various methods

Processing/tissue infiltration

Paraffin embedding

Slice microtomy

Hematoxylin and eosin staining

Special stains

Immunohistochemistry

OCT Embedding

Cryosectioning

Cytoprocessing

RNAScope in-situ hybridization

Diagnostic histology interpretation/microscopic evaluation

Tissue lesion scoring

Photography, gross and histologic

Digital Pathology

Stereological microscopy

CBC w/ differential, manual and automated

Reticulocyte

Platelet counts, manual and automated

Cytology

Sperm counts

Fluid analysis

Routine chemistry profile (13 tests + 2 calculations)

Whole chemistry profile (21 tests + 2 calculations)

Chemistry panels can be customized for any specific study

Glucose

BUN

Creatinine

Total protein

Albumin

Sodium

Potassium

Chloride

CO2

Calcium

Phosphorus

Cholesterol

Triglyceride

Total bilirubin

Alkaline phosphatase

GGT

ALT (SGPT)

AST (SGOT)

CK

LDH

Iron

Magnesium

CRP

Hemoglobin A1c

A wide menu of additional tests can be adapted to our DxC 700AU chemistry analyzer

Ova and parasites

Occult blood

Urinalysis with microscopic

Screens for Giardia, histolytica and C. parvum

Bacterial culture and sensitivity

PT (prothrombin time)

APTT (activated partial thromboplastin time)

Fibrinogen